Endocrine Abstracts

Background and Aims: Cardiometabolic comorbidity is a well-established complication related to GH hypersecretion. Several studies have highlighted an increased cardiovascular risk in this population. The objective of the current work was to investigate the cardiovascular complications in Tunisian patients diagnosed with acromegaly.Patients and Method: We conducted a retrospective study that included all patients diagnosed with acromegaly who have been fo...

Objective: Identify the risk factors of hypoparathyroidism (hypoPT) after Total thyroidectomy (TT).Patients and Methods: Our study is a randomised clinical trial. It enrolled patients who underwent total thyroidectomy at the department of ENT surgery at Habib Bourguiba Hospital in Sfax between November 2020 and august 2021. We studied age, gender, type of surgery, duration of surgery, vitamin D level, magnesium level, histopathological exam, inadvertent ...

Aim: The purposes of our study are to study the effect of systematic calcium and vitamin D supplementation on parathyroid glands function after total thyroidectomy.Patients and Methods: We conducted a prospective cohort study, including patients undergoing total thyroidectomy. Patients were randomly divided into two groups: group 1: with prophylactic supplementation (24 patients) and group 2: without prophylactic supplementation (23 patients). For each p...

Background/Aim: Since diabetes is the most common endocrine disorder and the diabetic ketoacidosis (DKA) is considered as a medical emergency, our aim was to determinate the frequency of symptoms and precipitating factors of DKA in type 1 and type 2 diabetesMethods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrinology Department for DKA between August 2021 to December 2022. We compared the di...

Background/Aims: Ketosis in patients with known Type 2 diabetes mellitus is overlooked due to atypical symptoms. Type 2 diabetes (DT2) is characterized by a longer period of asymptomatic hyperglycaemia than Type 1 diabetes(DT1). The objective of this study was to compare glycosylated haemoglobin (HbA1c) levels in ketoacidosis (DKA) occurring in known and newly diagnosed diabetes.Methods: This is a retrospective cross-sectional descriptive study concernin...

Background: Ramadan is the religious month in which Muslims fast from pre-dawn (suhoor) until sunset (iftar), abstaining from all kinds of food, and liquid. The major change in meal times may be challenging for hypothyroid patients on levothyroxine because levothyroxine has a narrow therapeutic index and should be taken on an empty stomach.Objective: We aim to compare pre- and post-Ramadan Thyroid function tests of hypothyroid patients taking levothyroxi...

Introduction: Thyroidectomy is a quite common procedure. Major postoperative complications of total thyroidectomy, including recurrent laryngeal nerve injur and hypocalcemia are not infrequent. The purpose of this study was to evaluate the incidence and risk factors of postoperative complications after total thyroidectomy.Methods: We retrospectively included patients who underwent total thyroidectomy over a period of 6 years. Hypocalcemia was defined as ...

Background: Diabetic retinopathy (DR) is a clinically well-defined sight-threatening complication in type 2 diabetes. Angiopoietin 1 (Ang1) has been shown to promote endothelial cell survival without causing proliferation, stabilise endothelial interactions with surrounding support cells and can block the vascular permeability effects of vascular endothelial growth factor (VEGF). More recent data suggest that balance between these growth factors may affect vascular endothelial...

Introduction: Hyperprolactinaemia can be caused by physiological changes, medications, pathological conditions, or can be idiopathic. The aim of this study was to evaluate clinicians's practice in ordering prolactin (PRL) test.MethodsA retrospective study concerning 75 prolactin requests data collected by the laboratory computer system (Health Lab) during January 2024. We collected age, sex and ordering's origins. PRL tests were performed based on electrochemiluminescence immu...

Background: Marine-Lenhart syndrome (MLS) is defined by the coexistence of Graves’ disease and a hyperactive nodule or multinodular goiter. Although rare, its diagnosis by functional imaging coupled with ultrasound is necessary in order to propose a radical treatment. We report the case of a patient followed for hyperthyroidism related to a SML.Case presentation: A 52-year-old patient consulted for a picture of thyrotoxicosis associating tremor, wei...